Does SimHub provide the HidStream by any chance?
On Windows, HIDSharp only raises that exception when it is doing an overlapped operation (Read, Write, etc.) and the "closed" event object has been set. In other words, it only says that when someone has called Close(), Dispose(), etc. on the stream.
I very intentionally do not track open HidStream objects from HidDevice, so there is no way for the library to call Close() on the stream. It has to be the user of the library. (HidDevice very intentionally has no setters, only getters and a method to open the stream. That way it can be cached, passed around freely, etc.) The whole library is designed to be thread-safe so that I can concurrently read and write from different threads, etc. so that should not be the problem.
As to access, HID devices, on Windows, Mac, and Linux, effectively share their read data between processes. There's no exclusivity, and any number of HID streams should be able to be open at the same time without problems. HID streams can't see what other processes are writing to the device, but all streams read back the device's responses.
I mention the HIDSharp exclusivity feature only because it's useful at times -- for example, if you are compiling and uploading to your device, you can use the exclusivity feature to block (and notify for interruption, actually, it supports that too) other parts/processes of your program (such as a device monitor or serial output tool) until the upload is complete. I use this extensively. But I don't think it'd help you at all with what you are describing.
There is actually one way you could catch the Close(). If you are using Visual Studio, use Debug->Attach To Process, and make sure the HidSharp PDB is there and you have HidSharp compiled in Debug mode, so that breakpoints work reliably. Navigate to a part of your code that calls Close() so that you can step into it, and set a breakpoint in WinHidStream.Dispose(bool disposing). Then next time you attach into the process, you'll have a breakpoint and can catch whatever is doing it.
Hope this helps.
God bless.
James